Antimicrobial Resistance (AMR) has emerged as a significant obstacle to the treatment of infectious diseases, it is crucial to find new medicines to combat the global rise of AMR. The cell membrane is a potential target for anti-bacterial therapy, serious damage to the cell membrane can initiate cell autophagy, apoptosis and necrosis. Antimicrobial peptides (AMPs) and cell-penetrating peptides (CPPs), are short amino acid sequences with antibacterial activity that can damage or penetrate the peripheral membrane to disrupt cell functions. Researchers in this study explore and discuss the potential of AMP and CPP to treat microbial infections due to their capacities to enhance drug bioavailability and improve therapeutic efficiency.
Link to the Article: rb.gy/lexez5
Published On: 24/03/2023