Damaged microbiota is involved in chronic inflammatory diseases, psychiatric diseases, and some bacterial or viral infections.
Researchers have found recent evidences that show microbiota is evidently altered in patients with viral infections such as post-acute COVID-19 syndrome (PACS).
Depending on the impact of COVID-19 on the microbiota, there are different immune response of the body, microbiome analysis could hence be a strategy to predict the development of specific long-lasting symptoms. In addition, modulation of the microbiota could facilitate recovery from post-acute COVID-19 syndrome. The damage and alterations that the microbiota can have during COVID-19 along with massively used antibiotics can have a detrimental effect on the body’s homeostasis. A targeted microbial approach could lead to intestinal eubiosis to better facilitate recovery from the disease and subsequent symptoms of COVID-19. A correlation between cytokine secretion and the state of the human gut microbiome was observed, thus suggesting that therapies can inhibit or enhance certain microbiota. Prebiotics, probiotics, postbiotics, synbiotics, microbiota transplantation and bacteriophages, could assume an additional and supplementary role in the treatment of pandemic infection through inhibition of the inflammatory state caused by cytokines.
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Published On: 11/02/2023