The explosion of microbiome research over the past decade has shed light on various ways that external factors interact with human microbiome to drive health and disease. Gut microbiome is sensitive to exposure of environmental toxicants and diet patterns that biologically mediates their positive and negative effects on human health. Imbalances of gut microbiome have been associated with various disorders, including obesity, diabetes and inflammatory bowel disease. A better understanding of how dietary components can impact gut microbiome and human health is crucial for improving food safety risk assessment. Food and Agricultural Organization of the United Nation conducted a review of the literature to assess the scientific evidence regarding the impact of microplastics, and residues of pesticide and veterinary drugs on gut microbiome and their potential connection to adverse health effects. The focus of the review was on food safety, aiming to identify research limitations, knowledge gaps and areas that need further investigation before using gut microbiome data in chemical evaluations and ultimately advancing food safety risk assessment.
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Published On: /05/2023