This study delves into the dynamic interactions between the host’s genetics and the gut microbiome, focusing on how structural variations (SVs) in the microbial genome can be influenced by genetic factors and environmental conditions. These interactions have significant implications for…
The interplay between the gut microbiota and various behavioral conditions, including food addiction, is an area of scientific interest. Food addiction is a multifactorial behavioral disorder characterized by compulsive eating behaviors and a loss of control over food intake, closely…
Antimicrobial resistance (AMR) poses a significant global health threat, necessitating precise identification and management strategies. This study explores a novel approach using transcriptomics and machine learning to predict antibiotic resistance profiles in pathogens, aiming to enhance treatment efficacy and combat…
The human gut microbiome is made up of an extensive range of bacteria that have an impact on many physiological processes, such as metabolism, immunological response, and neurological disorders. G protein-coupled receptors (GPCRs), a key type of membrane receptors involved…
Hyperthermia induced by phenethylamines like 3,4-methylenedioxymethamphetamine (MDMA) can lead to severe health complications and death. The sympathetic nervous system’s activation and norepinephrine release have been implicated in this condition. The gut microbiome and its production of bile acids (BAs) may…
The emergence of antimicrobial tolerance and resistance presents a significant challenge to global public health, particularly due to the persistence of bacterial cells that can survive antibiotic treatments. This study systematically explores the interactions between various metabolic inhibitors—such as chloramphenicol…
Obesity, a global health concern, commonly linked to an imbalance between energy intake and expenditure. Even among individuals with comparable living conditions and eating habits, there are notable individual differences in their susceptibility to obesity. Using male C57BL/6J mouse models,…
The rapid rise of antibiotic resistance, coupled with the slow discovery of new antibiotics, poses a significant threat to global health. We truly require new antibacterial medicines since infections are become more and more resistant to drugs. Phage lysins have…
Birth by caesarean section (CS) has been associated with altered gut microbiome development and an increased risk of certain diseases later in life. This has led to interest in interventions to restore the gut microbiome of CS-born infants to resemble…
Plenty of people rely on the rejuvenating properties of coffee to get them through the morning and start their day. In addition to its well-known stimulant qualities, coffee can have a major effect on your gut microbiota. Your overall health…
The complex interactions between host-produced hormones and human-associated bacteria have been brought to light by recent studies, but the underlying processes and physiological effects are still mostly unknown. This study focuses on the gut bacteria Gordonibacter pamelaeae and Eggerthella lenta,…
Alzheimer’s disease (AD) is a prominent neurological disorder that predominantly impacts older people. It is also the primary cause of dementia. Given that aging is a major risk factor for AD, it is imperative that the disease be identified early…