Month January 2024

๐๐ก๐š๐ ๐ž๐จ๐ฆ๐ž ๐ƒ๐ฒ๐ง๐š๐ฆ๐ข๐œ๐ฌ ๐ข๐ง ๐…๐ž๐œ๐š๐ฅ ๐Œ๐ข๐œ๐ซ๐จ๐›๐ข๐จ๐ญ๐š ๐“๐ซ๐š๐ง๐ฌ๐ฉ๐ฅ๐š๐ง๐ญ๐š๐ญ๐ข๐จ๐ง: ๐ˆ๐ง๐ฌ๐ข๐ ๐ก๐ญ๐ฌ ๐Ÿ๐ซ๐จ๐ฆ ๐ญ๐ก๐ž ๐†๐ฎ๐ญ ๐๐ฎ๐ ๐ฌ ๐“๐ซ๐ข๐š๐ฅ

๐Ÿ’ก Fecal Microbiota Transplantation (FMT) is a therapeutic intervention that modulates the gut microbiome to treat various health conditions. While the impact of FMT on bacterial communities has been studied, its influence on the phageome remains unclear. This study, conductedโ€ฆ

๐€ ๐ซ๐จ๐›๐ฎ๐ฌ๐ญ ๐ฆ๐ข๐œ๐ซ๐จ๐›๐ข๐จ๐ฆ๐ž ๐ฌ๐ข๐ ๐ง๐š๐ญ๐ฎ๐ซ๐ž ๐Ÿ๐จ๐ซ ๐š๐ฎ๐ญ๐ข๐ฌ๐ฆ ๐ฌ๐ฉ๐ž๐œ๐ญ๐ซ๐ฎ๐ฆ ๐๐ข๐ฌ๐จ๐ซ๐๐ž๐ซ ๐š๐œ๐ซ๐จ๐ฌ๐ฌ ๐๐ข๐Ÿ๐Ÿ๐ž๐ซ๐ž๐ง๐ญ ๐ฌ๐ญ๐ฎ๐๐ข๐ž๐ฌ ๐ฎ๐ฌ๐ข๐ง๐  ๐ฆ๐š๐œ๐ก๐ข๐ง๐ž ๐ฅ๐ž๐š๐ซ๐ง๐ข๐ง๐ 

๐Ÿ’ก Autism Spectrum Disorder (ASD) is characterized by neurodevelopmental deficits, with emerging evidence implicating the gut microbiome in its pathophysiology. This study employs a machine learning approach to identify bacterial taxa associated with ASD and validate their predictive power acrossโ€ฆ

Longitudinal profiling of the intestinal microbiome in children with cystic fibrosis treated with elexacaftor-tezacaftor-ivacaftor

๐Ÿ’ก This single-center longitudinal analysis investigates the effects of ELX/TEZ/IVA on the intestinal microbiome, inflammation, and clinical parameters in children with cystic fibrosis (CF). The study reveals significant improvements in body mass index (BMI), forced expiratory volume in one secondโ€ฆ

The Gut Puzzle: Factors Shaping Microbes

The human gut is a complex ecosystem hosting trillions of microorganisms, known as the gut microbiota. This dynamic community has a significant impact on human health, regulating different physiological systems such as digestion, metabolism, and immunological function. Understanding the mechanismsโ€ฆ

๐Œ๐ž๐ญ๐š๐›๐จ๐ฅ๐จ๐ฆ๐ข๐œ ๐€๐ง๐š๐ฅ๐ฒ๐ฌ๐ข๐ฌ ๐จ๐Ÿ ๐Œ๐ž๐œ๐จ๐ง๐ข๐ฎ๐ฆ ๐š๐ง๐ ๐’๐ญ๐จ๐จ๐ฅ ๐ข๐ง ๐๐ซ๐ž๐ญ๐ž๐ซ๐ฆ ๐๐ž๐ฐ๐›๐จ๐ซ๐ง๐ฌ: ๐ˆ๐ง๐ฌ๐ข๐ ๐ก๐ญ๐ฌ ๐ข๐ง๐ญ๐จ ๐Œ๐ข๐œ๐ซ๐จ๐›๐ข๐š๐ฅ ๐ˆ๐ง๐Ÿ๐ฅ๐ฎ๐ž๐ง๐œ๐ž๐ฌ ๐š๐ง๐ ๐†๐ž๐ง๐๐ž๐ซ-๐‘๐ž๐ฅ๐š๐ญ๐ž๐ ๐Œ๐ž๐ญ๐š๐›๐จ๐ฅ๐ข๐ญ๐ž ๐•๐š๐ซ๐ข๐š๐ญ๐ข๐จ๐ง๐ฌ

๐Ÿ’ก This study employs High-Resolution Proton Nuclear Magnetic Resonance (1H HR NMR) metabolomic analysis to investigate the metabolite profiles of meconium and stool samples from preterm newborns. The research aims to assess the feasibility of NMR in understanding the metabolicโ€ฆ

๐ˆ๐ฆ๐ฉ๐š๐œ๐ญ ๐จ๐Ÿ ๐‹๐ข๐ง๐š๐œ๐ฅ๐จ๐ญ๐ข๐๐ž ๐จ๐ง ๐†๐ฎ๐ญ ๐Œ๐ข๐œ๐ซ๐จ๐›๐ข๐จ๐ญ๐š ๐‚๐จ๐ฆ๐ฉ๐จ๐ฌ๐ข๐ญ๐ข๐จ๐ง ๐š๐ง๐ ๐„๐Ÿ๐Ÿ๐ข๐œ๐š๐œ๐ฒ ๐ข๐ง ๐ˆ๐ซ๐ซ๐ข๐ญ๐š๐›๐ฅ๐ž ๐๐จ๐ฐ๐ž๐ฅ ๐’๐ฒ๐ง๐๐ซ๐จ๐ฆ๐ž ๐ฐ๐ข๐ญ๐ก ๐‚๐จ๐ง๐ฌ๐ญ๐ข๐ฉ๐š๐ญ๐ข๐จ๐ง (๐ˆ๐๐’-๐‚) ๐๐š๐ญ๐ข๐ž๐ง๐ญ๐ฌ

๐Ÿ’ก This scientific report investigates the influence of linaclotide, a therapeutic agent for Irritable Bowel Syndrome with Constipation (IBS-C), on gut microbiota composition and its correlation with treatment efficacy. The study highlights the association between changes in the gut microbiome,โ€ฆ

๐‚๐จ๐š๐๐ฆ๐ข๐ง๐ข๐ฌ๐ญ๐ซ๐š๐ญ๐ข๐จ๐ง ๐จ๐Ÿ ๐๐ซ๐จ๐›๐ข๐จ๐ญ๐ข๐œ๐ฌ ๐–๐ข๐ญ๐ก ๐€๐ง๐ญ๐ข๐›๐ข๐จ๐ญ๐ข๐œ๐ฌ

๐Ÿ’ก This scientific report delves into the multifaceted applications of probiotics as living microorganisms in conjunction with antibiotic therapy. The study explores their impact on microbial adhesion, immunomodulation, intestinal barrier integrity, and the recovery of commensal microbiota, emphasizing their overallโ€ฆ

Effect of altered gene expression in lipid metabolism on cognitive improvement in patients with Alzheimerโ€™s dementia following fecal microbiota transplantation: a preliminary study

๐Ÿ’ก This study investigates the impact of Fecal Microbiota Transplantation (FMT) on cognitive function in Alzheimerโ€™s dementia (AD) patients and explores the intricate relationship between cognition, gut microbiota alterations, and gene expression changes. The findings provide compelling evidence of FMTโ€™sโ€ฆ

ย ๐ˆ๐ฆ๐ฉ๐š๐œ๐ญ ๐จ๐Ÿ ๐‡๐ˆ๐• ๐„๐ฑ๐ฉ๐จ๐ฌ๐ฎ๐ซ๐ž ๐จ๐ง ๐ˆ๐ง๐Ÿ๐š๐ง๐ญ ๐†๐ฎ๐ญ ๐Œ๐ข๐œ๐ซ๐จ๐›๐ข๐จ๐ญ๐š ๐š๐ง๐ ๐ข๐ญ๐ฌ ๐€๐ฌ๐ฌ๐จ๐œ๐ข๐š๐ญ๐ข๐จ๐ง ๐ฐ๐ข๐ญ๐ก ๐“๐ž๐ญ๐š๐ง๐ฎ๐ฌ ๐“๐จ๐ฑ๐จ๐ข๐ ๐•๐š๐œ๐œ๐ข๐ง๐ž ๐‘๐ž๐ฌ๐ฉ๐จ๐ง๐ฌ๐ž๐ฌย 

๐Ÿ’ก This study investigates the influence of HIV exposure on the gut microbiota of infants and its potential association with humoral responses to tetanus toxoid (TT) vaccination. Examining 278 infants from South Africa and Nigeria, with varying HIV exposure statuses,โ€ฆ