Month October 2023

💡 This comprehensive review explores the intricate interplay between the gut microbiome and the central nervous system (CNS), with a specific focus on microglial cells. Notably, prenatal maternal microbiome and diet are identified as early influencers of microglial activity, which…

💡 This study delves into the association between gut dysbiosis and all-cause, as well as cause-specific mortality, within the context of solid organ transplant recipients (SOTR). 📌 The study employed multivariable Cox regression and machine learning to identify gut dysbiosis…

💡 This study aimed to investigate the neuroprotective potential of cyanidin-3-O-glucoside (C3G), a prevalent anthocyanin in human diets, against TMT-induced neurodegeneration and cognitive impairment. 📌 The study sheds light on the multifaceted mechanisms underlying the neuroprotective effects of C3G and…

💡 This study systematically assessed the distribution and ecological implications of amino acid auxotrophies within the human gut microbiome. 📌 Metabolic cross-feeding interactions among coexisting genotypes were proposed as a potential source for amino acids, underscoring the ecological relevance of…

📌 Delirium is a common clinical syndrome characterized by an acute change in attention, awareness, and cognition, frequently observed in older patients during hospitalization for acute medical illness or after surgery. 💡 This study provides a detailed analysis of the…

💡 The human gut microbiome plays a crucial role in modulating the balance between pro-inflammatory and anti-inflammatory responses in the gastrointestinal tract. This study aimed to unravel the intricate interactions between dietary factors, gut microbiota, and their functional capacity to…

💡 This study presents a secondary analysis of a randomized, double-blinded, placebo-controlled trial conducted in children aged 6-59 months with severe acute malnutrition (SAM) who were treated as outpatients in Madarounfa, Niger. 📌 The study aimed to assess the acute…

💡 This study delves into the introduction and application of a novel Metabolite Exchange Score (MES) to assess cross-feeding interactions within the human gut microbiome. 📌 Using metabolic models of prokaryotic metagenome-assembled genomes from a vast dataset encompassing 11 disease…